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Online Liposome Extruder

Description: Genizer Online Liposome Extruders can be connected with a sanitary pump or high pressure homogenizer and are temperature controlled, from testing to manufacturing production of liposomes and lipopolyplex, for drug and gene delivery.
Catalog Number: Cat.GOE
Price:
USD
$1,000.00   Login for Discount
Online Liposome Extruder
Online Liposome Extruder
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  • Catalog No.:
    GOE-25mL GOE-200mL GOE-1000mL GOE-8L GOE-20L GOE-8L×2 GOE-8L×4 GOE-8L×6
  • Warranty:
    Standard 1 year
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  • Description
Specifications
Description:
 
Genizer Online Liposome Extruders can be connected with a sanitary pump or high pressure homogenizer and are temperature controlled, from testing to manufacturing production of pharmaceutical liposomes for anti-cancer drugs. Homogeneous samples can be produced quickly and easily in minutes; typically 5-10 passes are sufficient to produce a sample with uniform liposome size. Genizer Online Liposome Extruders are designed to generate homogeneous unilamellar liposomes and lipopolyplex. Extrusion is a one-step procedure that produces liposomes by forcing lipid suspensions of drug, protein or gene through track-etched filters of defined pore size. The Online Liposome Extruder offers virtually no dead volume, is easy to clean, suitable for sterilization and in compliance with FDA and GMP sanitary standards in pharmaceuticals.
 
Application:
 
Liposome extrusion; Sterile filtration
 
Performance:
 
No dead volume
Online extruder can control the temperature of extrusion
 
Specifications
Catalog No. GOE-25mL GOE-200mL GOE-1000mL GOE-8L GOE-20L
Sample Size 25 mL 200 mL 1000 mL 8000 mL 20000 mL
Cooling Jacketed Jacketed Jacketed Jacketed Jacketed
Dimensions 10 cm×10 cm×8 cm 13 cm×13 cm×9 cm 18 cm×18 cm×10 cm 25 cm×30 cm×25 cm 40 cm×45 cm×30 cm
Weight 1 kg 2 kg 5 kg 24.5 kg 120 kg
Min. Sample Size 5 mL 10 mL 100 mL 200 mL 1000 mL
Max. Pressure 3, 000 psi 3, 000 psi 2, 500 psi 2, 500 psi 2, 500 psi
Max. Temp. 80 ºC (176 ºF)
Power Type High pressure pump or high pressure homogenizer
Cleaning Disassemble, rinse, clean, and dry
Sterilization Whole unit autoclavable
 
Standard Features
Parts Liposome Online Extruder
316L Stainless Steel Filter Plate Sintered Plate (20um φ25) Sintered Plate (20um φ47) Sintered Plate (20um φ90) Sintered Plate (20um φ142) Sintered Plate (20um φ293)
Drain Disc sold separately
Liposome Membrane sold separately
Inlet Type HF4 HF4 HF4 HF6 HF9
Outlet Type Luer Type Luer Type Luer Type Luer Type Barbed Type
Handle No No No Yes Yes
Automatic Lifting No No No No Yes
Product Material 316L stainless steel, NBR
Material Standard Sanitary grade; compliant with FDA and GMP sanitary standards
 
Option Features
Detector Sanitary pressure gauge with adaptor, pressure transducer, temperature transducer
Liposome Membrane φ25 (30, 50, 80, 200, 400, 800nm, 1um, 2μm, 5μm, 10μm) φ47 (30, 50, 80, 200, 400, 800nm, 1um, 2μm, 5μm, 10μm) φ90 (30, 50, 80, 200, 400, 800nm, 1um, 2μm, 5μm, 10μm) φ142 (30, 50, 80, 200, 400, 800nm, 1um, 2μm, 5μm, 10μm) φ293 (30, 50, 80, 200, 400, 800nm, 1um, 2μm, 5μm, 10μm)
Sintered Plate φ25 (5μm, 10μm, 20μm) φ47 (5μm, 10μm, 20μm) φ90 (5μm, 10μm, 20 μm) φ142 (5μm, 10μm, 20μm) φ293 (5μm, 10μm, 20μm)
O-ring NBR；FKM；FFKM
Power Type High pressure pump, high pressure homogenizer or hand pump
CIP/SIP Customizable (not compatible with drain disc)
Sanitary High-Pressure Flexible Hose Customizable
Outlet Type Customizable barbed type
Multi Extruder Parallel or series connection of multi-extruder
URS for Liposome Extruders System.doc