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High Pressure Micromix Homogenizer MixGenizer

Description: A homogenizer designed especially for mixing and homogenizing the sample fluids from two or more inlet ports.
Catalog Number: MixGenizer
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  • Pressure:
    30,000psi
  • Flow Rate:
    100mL/min
  • Chamber:
    Diamond Mixing Chamber Diamond Mixing Chamber-RT
  • Syringe Inlet&Outlet:
    20mL*3 50mL*3 100mL*3 200mL*3
  • Option: Inlet Stainless Cylinder:
    None 500mL 1000mL 2000mL 300mL-Glass-Jacketed 300mL
  • Option: Heat Exchanger:
    None HPE-100 HPE-150 HPE-150-3D
  • Voltage:
    110V 220V
  • Warranty:
    Standard 1 year 2 year 3 year 4 year 5 year
  • IQ/OQ Installation and Operational Qualification:
    N/A IQ/OQ
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  • Description
  • How to Use
  • FAQs and Tips
  • How to Order
Description:
A homogenizer designed especially for mixing and homogenizing the sample fluids from two or more inlet ports.
 
Application:
Nanodispersions, nanoemulsions and nanotube
Cell disruption
Micro/nanoencapsulation in polymers, liposomes and oils
Solid dispersion and suspension, deagglomeration
 
Performance:
Energy efficient, 1/2 energy loss of the most homogenizers
Small (integrated design delivers the light weight and small dimensions)
Smart (programming control systems confer diligent functions: controlled inlet volume ± 0.1mL; auto stop with time/volume)
Silent (noiseless performance)
Strong (more than 100 mL/min at 30,000 psi)
CE compliant and RoHs compliant
 
Specifications
Catalog No. MixGenizer-30k
Max. Flow Rate 100mL/min
Min. Sample 1mL
Max. Pressure 30,000psi
Dimensions(cm) 85×50×35
Weight 58kg (128lbs)  
Max. Temp. 80ºC (176ºF)
Power 220V/110V
Cleaning Flush to clean
Application Nano emulsion, fat emulsion, liposome, cell disruption, nano dispersion, deagglomeration, nano precipitations
Features Notable shear rate; powerful micromix; greater repeatability; guaranteed scalability
 
Standard Features
Parts Y-type diamond mixing chamber 
Control System High pressure programming control systems®: touch screen, speed control, auto stop control by volume, time, pressure or temperature, settable volume control as small as 1mL, display of flow rate and time, overload protection
Pressure Gauge Digital display on the touch screen
Inlet Type 1/4" HP coupling
Outlet Type 1/4" HP coupling
Inlet Speed 0-100mL/min ± 0.1mL/min
Mixing Accuracy 1%
Mixing Arrange 25%-100%
Inlet Reservoir 20mL syringe or S/S cylinder
Outlet Reservoir 20mL syringe or S/S cylinder
Product Material 316L stainless steel, tungsten carbide, viton, teflon
Material Standard Pharmaceutical grade, FDA, GMP
Warranty 1 year against any manufacturing defects
 
Option Features
Parts High pressure extruders, Y-type diamond mixing chamber with cooling, heat exchanger
Control System Gradient mixing, three or four component
Detector Pressure gauge, pressure transducer up to 8 optional, temperature transducer up to 8 optional
Outlet Type Tri-clamp, luer or flow sorter
Heat Exchanger HPE-100-3D; HPE-150-3D; HPE-200-3D
Inlet Reservoir 20mL, 50mL, 100mL, 200mL syringe, 300mL, 500mL S/S cylinder, jacketed glass cylinder or online 
Outlet Reservoir 20mL, 50mL, 100mL, 200mL syringe, 300mL, 500mL S/S cylinder, jacketed glass cylinder or online 
Cylinder Titanium high pressure cylinder (resistant to strong acid and base)
 
Varieties of Inlet and Outlet for MixGenizer
Inlet:  syringe; open container; stainless steel cylinder
Outlet: syringe; open container; stainless steel cylinder
Inlet and outlet
Genizer's flow Sorter for MixGenizer can collect samples with designed pressure or volumn.

High Pressure Micromix Homogenizer MixGenizer
A flow sorter allows the user to select (gate) on a flow of pressure or volumn.
A user can set the the pressure, so the mixed sample above the pressure and mixed sample under the pressure can be seperated.
A user can also set the percentage of volumn, so the mixed sample within the percentage of volumn and mixed sample outside 
the percentage of volumn can be seperated.
Troubleshooting:
Our design has minimized the occurrence of  air-blocking, chamber-blocking and overload.
However, the improper operation of the homogenizer can still induce the errors and cause damage to the homogenizer.

Air Blocking
Symptom: there is no pressure and no sucking from inlet
Prevention: do not run with empty inlet
Reason: there is air inside the pump
Solutions:
1) In the customer setup, push the button called Degas
2) Running 50mL water with 50% speed
3) Push the ball into the inlet valve with a pin
Push the ball into the inlet valve with a pin

Chamber Blocking
Symptom: overload of the pressure
Prevention: pre-treat the sample carefully; reduce the speed
Reason: there are aggregates or particles in the sample; too high a speed
Solutions:
1) Reverse flow the outlet valve with 100mL water with low speed
2) Reverse flow the chamber with water from low to high speed

Overload
Solutions:
1) Reduce the speed and close the power, wait 30 sec and restart 
2) Wash with water or solvent
3) Run with clean and homo-disperse sample

No Response
Symptom: the equipment does not respond when click the “Start” button on the touch screen
Solutions: 
1) Turn off the power supply and wait for 30 seconds to restart
2) If there is still no response, please check the power input. The power supply of the equipment is 220V. When the external power supply is 110V, a power converter shall be used. And its INPUT port should connect to 110V while the OUTPUT port connect to 220V

Air blocking rarely causes damage to the NanoGenizer; however, the chamber blocking is harmful to the pump because of overloaded pressure in an instant.
1) Pretreat the sample carefully, and always use a clean and homo-disperse sample
2) Adjust the pressure from low to high
3) For safety, do not point the inlet or outlet of high pressure devices and equipment supplied by Genizer, including high pressure homogenizer, extruder, interaction chamber and valve, to any personnel or object that may affect safety or induce property loss.

Tips:
For facilitating the user applications, the two ports in the high pressure cylinder of the NanoGenizer are exchangeable for inlet and outlet.


PRESSURE AND CHAMBER SELECTION FOR VARIOUS APPLICATIONS with NANOGENIZER
Cells Mammalian cell
Mammalian cell
Insect cellInsect cell Bacteria cellBacteria cell Yeast cellYeast cell Algae cellAlgae cell Spore
Spore
Sample CHO|Hela Sf9|Sf21|H5 E. Coli   Yeast Green algaea Ganoderma
Pressure 600-800bar   8500-11500psi 600-1000bar 8500-14500psi 800-1000bar 11500-14500psi 1200-1400bar 17500-20000psi 1200-1500bar 7500-21500psi 1300-1600bar 18500-23000psi
Chamber F20Y, F20Y-RT F20Y, F20Y-RT F20Y, F20Y-RT F20Y, F12Y F20Y, F12Y F20Y, F12Y












 
Emulsions Oil in water emulsions
Fat emulsion| Prostaglandin
Water in oil emulsionsCosmetics Oil emulsionDimethicone|Fuel FoodMilk Liposome (o/w)Doxorubicin Liposome (w/o)
DNA|lipopolyplex
Sample Fat emulsion| Prostaglandin Cosmetics Dimethicone|Fuel Milk Doxorubicin DNA|lipopolyplex
Pressure ~20,000psi ~10,000psi ~20,000psi ~10,000psi ~20,000psi ~8,000psi
Chamber F20Y, F12Y F20Y F20Y, F12Y F20Y F20Y, F12Y F20Y
















 
Dispersions Pigments
Inks, Coatings
Drugs/CreamsNorfloxacin, Isoxyl BatteryLithium/Solar cell Particle aggregationNano fibril GrapheneGraphene Nanotubes
Carbon Nanotubes
Sample Inks, Coatings Norfloxacin, Isoxyl Lithium/Solar cell Nano fibril Graphene Carbon Nanotubes
Pressure ~25,000psi ~20,000psi ~20,000psi ~25,000psi ~20,000psi ~20,000psi
Chamber F20Y, F12Y F20Y, F12Y F20Y, F12Y F20Y, F12Y F20Y, F12Y F20Y, F12Y
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4. Order and pay online from the website if the total amount exceeds $3,000.00.