Nano High Pressure Homogenizer NanoGenizer-Ⅱ

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NanoGenizer Series High Pressure Homogenizer

Nanogenizer High Pressure Homogenizer Manual

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Pressure:
15,000psi 20,000psi 25,000psi 30,000psi 35,000psi 40,000psi 45,000psi
Flow Rate:
60mL/min 100mL/min 120mL/min 150mL/min 180mL/min 200mL/min 230mL/min
Syringe Inlet&Outlet:
20mL*2 30mL*2 50mL*2 100mL*2 300mL*2
Option: Inlet Stainless Cylinder:
None 500mL 1000mL 2000mL 300mL-Glass-Jacketed
Option: Heat Exchanger:
None HPE-100 HPE-150 HPE-150-3D
Voltage:
110V 220V
Warranty:
Standard 1 year 2 year 3 year 4 year 5 year
Compliance:
N/A IQ/OQ
Ships From:
China

Description
How to Use
FAQs and Tips
How to Order

NanoGenizer High Pressure Homogenizer:

NanoGenizer is a laboratory high pressure processing device. It is an electrically-driven and bench-top, high pressure homogenizer requiring no compressed air or hydraulic oil to achieve maximum 3,062 bar (45,000 psi) operating pressure.
NanoGenizer high pressure homogenizer is composed of a feed reservoir, high pressure pump, transducer, PLC control panel and microfluidics diamond interaction chamber. The sanitary pump system of the NanoGenizer high pressure homogenizer is able to supply the desired pressure to the product stream and push it through the micron chamber (microreactor) to create high shear rates and strong impact within the stream. This process results in uniform particle distribution and smaller particle sizes.

Application of NanoGenizer High Pressure Homogenizer:

Cell disruption and particle size reduction
Nanoemulsions
Nano dispersions
Liposomes
Deagglomeration

Performance of NanoGenizer High Pressure Homogenizer:

Energy efficient, 1/2 energy loss of the most homogenizers
Small (integrated design delivers the light weight and small dimensions)
Smart (programming control systems confer diligent functions: controlled inlet volume ± 0.1mL; auto stop with time/volume)
Silent (noiseless performance)
Strong (more than 150 mL/min at 30,000 psi)
CE compliant and RoHS compliant

Specifications
Catalog No.	NG-15K	NG-20K	NG-25K	NG-30K	NG-45K
Flow Rate	150mL/min	150mL/min	100mL/min	100mL/min	60mL/min
Min. Sample	5mL	5mL	5mL	5mL	5mL
Max. Pressure	15,000psi	20,000psi	25,000psi	30,000psi	45,000psi
Dimensions(cm)	70 × 36 × 30	70 × 36 × 30	70 × 36 × 30	70 × 36 × 30	70 × 36 × 30
Weight	35 kg (75 lbs)	35 kg (75 lbs)	35 kg (75 lbs)	35 kg (75 lbs)	35 kg (75 lbs)
Max. Temp.	80ºC (176ºF)
Power	110V/220V
Cleaning	Flush to clean
Application	Nano emulsion, fat emulsion, liposome, cell disruption, nano dispersion, deagglomeration
Features	Digital display of pressure or pressure gauge

Standard Features
Parts	Y-type diamond interaction chamber with cooling option
Control System	High pressure programming control systems: touch screen, speed control, auto stop control by volume, time, pressure or temperature, settable volume control as low as 1mL, display of flow rate and time, overload protection
Pressure Gauge	Digital display on the touch screen
Inlet Type	1/4" HP coupling
Outlet Type	1/4" HP coupling
Inlet Reservoir	20mL syringe
Outlet Reservoir	20mL syringe
Product Material	316L stainless steel, tungsten carbide, viton, teflon
Material Standard	Sanitary grade, FDA, GMP
Warranty	1 year against any manufacturing defects

Option Features
Parts	High pressure extruders, homogenizing valves, heat exchanger
Control System	Mechanical control: speed, start, stop control
Detector	Pressure gauge, pressure transducer, temperature transducer<
Outlet type	Tri-clamp or luer
Heat Exchanger	HPE-100-3D; HPE-150-3D; HPE-200-3D
Liposome Extruder	GOE-200mL; GOE-1000mL
Inlet Reservoir	10mL, 20mL, 50mL, 100mL, 200mL, 500mL syringe, S/S cylinder, jacketed glass cylinder or online
Outlet Reservoir	10mL, 20mL, 50mL, 100mL, 200mL, 500mL syringe, S/S cylinder, jacketed glass cylinder or online
Cylinder	Titanium high pressure cylinder (resistant to strong acid and base)

Product Introduction and User Guide Video Sharing: User guide of genizer highpressure homogenizers Introduces the structure and operation of the microjet high-pressure homogenizer

Varieties of Inlet and Outlet for NanoGenizer

Inlet: syringe; open container; stainless steel cylinder
Outlet: syringe; open container; stainless steel cylinder

High Pressure Homogenizer Inlet and Outlet

Troubleshooting:
Our design has minimized the occurrence of air-blocking, chamber-blocking and overload.
However, the improper operation of the homogenizer can still induce errors and cause damage to the homogenizer.

Air Blocking
Symptom: there is no pressure and no sucking from inlet
Prevention: do not run with empty inlet
Reason: there is air inside the pump
Solutions:
1) In the customer setup, push the "Degas" button
2) Running 50mL water with 50% speed
3) Push the ball into the inlet valve with a pin

Push the ball into the inlet valve with a pin

Chamber Blocking
Symptom: overload of the pressure
Prevention: pre-treat the sample carefully; reduce the speed
Reason: there are aggregates or particles in the sample; too high a speed
Solutions:
1) Reverse flow the outlet valve with 100mL water with low speed
2) Reverse flow the chamber with water from low to high speed

Overload
Solutions:
1) Reduce the speed and close the power, wait 30 sec and restart
2) Wash with water or solvent
3) Run with clean and homo-disperse sample

No Response
Symptom: the equipment does not respond when click the “Start” button on the touch screen
Solutions:
1) Turn off the power supply and wait for 30 sec to restart
2) If there is still no response, please check the power input. The power supply of the equipment is 220V. When the external power supply is 110V, a power converter shall be used. And its INPUT port should connect to 110V while the OUTPUT port connect to 220V

Air blocking rarely causes damage to the NanoGenizer; however, the chamber blocking is harmful to the pump because of overloaded pressure in an instant.
1) Pretreat the sample carefully, and always use a clean and homo-disperse sample
2) Adjust the pressure from low to high
3) For safety, do not point the inlet or outlet of high pressure devices and equipment supplied by Genizer, including high pressure homogenizer, extruder, interaction chamber and valve, to any personnel or object that may affect safety or induce property loss.

Tips:
For facilitating the user applications, the two ports in the high pressure cylinder of the NanoGenizer are exchangeable for inlet and outlet.

Pressure and chamber selection for various applications with NanoGenizer

Cells	Mammalian cell	Insect cell	Bacteria cell	Yeast cell	Algae cell	Spore
Sample	CHO\|Hela	Sf9\|Sf21\|H5	E. Coli	Yeast	Green algae	Ganoderma
Pressure	600-800bar 8500-11500psi	600-1000bar 8500-14500psi	800-1000bar 11500-14500psi	1200-1400bar 17500-20000psi	1200-1500bar 7500-21500psi	1300-1600bar 18500-23000psi
Chamber	F20Y, F20Y-RT	F20Y, F20Y-RT	F20Y, F20Y-RT	F20Y, F12Y	F20Y, F12Y	F20Y, F12Y

Emulsions	Oil in water emulsions	Water in oil emulsions	Oil emulsion	Food	Liposome (o/w)	Liposome (w/o)
Sample	Fat emulsion	Cosmetics	Fuel	Milk	DOX	DNA\|lipopolyplex
Pressure	~20,000psi	~10,000psi	~20,000psi	~10,000psi	~20,000psi	~8,000psi
Chamber	F20Y, F12Y	F20Y	F20Y, F12Y	F20Y	F20Y, F12Y	F20Y

Dispersions	Pigments	Creams	Battery	Particle aggregation	Graphene	Nanotubes
Sample	Inks, Coatings	Creams	Lithium/Solar cell	Nano fibril	Graphene	Carbon Nanotubes
Pressure	~25,000psi	~20,000psi	~20,000psi	~25,000psi	~20,000psi	~20,000psi
Chamber	F20Y, F12Y	F20Y, F12Y	F20Y, F12Y	F20Y, F12Y	F20Y, F12Y	F20Y, F12Y

Nano High Pressure Homogenizer NanoGenizer-Ⅱ

Pressure:

Flow Rate:

Syringe Inlet&Outlet:

Option: Inlet Stainless Cylinder:

Option: Heat Exchanger:

Voltage:

Warranty:

Compliance:

Ships From:

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